Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors

Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors

Kostrikov et al. report a deficiency of transcardial perfusion in brain tumor vasculature, which leads to exaggeration of drug extravasation measurements. They then demonstrate how optical tissue clearing can help to overcome this limitation and provide two machine learning-based image analysis work...

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Bibliographic Details
Main Authors: Serhii Kostrikov, Kasper B. Johnsen, Thomas H. Braunstein, Johann M. Gudbergsson, Frederikke P. Fliedner, Elisabeth A. A. Obara, Petra Hamerlik, Anders E. Hansen, Andreas Kjaer, Casper Hempel, Thomas L. Andresen
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02275-y

Internet

https://doi.org/10.1038/s42003-021-02275-y

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