Calcium: alpha-synuclein interactions in alpha-synucleinopathies

Aggregation of the pre-synaptic protein, α-synuclein (α-syn), is the key aetiological factor in Parkinson’s disease (PD) and other alpha-synucleinopathies, such as multiple system atrophy and Dementia with Lewy bodies. Various triggers for pathological α-syn aggregation have been elucidated, includi...

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Bibliographic Details
Main Authors: Alexandre N. Rcom-H’cheo-Gauthier1, Samantha L. Osborne, Adrian C.B. Meedneniya, Dean Louis Pountney
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00570/full