Continuing Exposure to Low-Dose Nonylphenol Aggravates Adenine-Induced Chronic Renal Dysfunction and Role of Rosuvastatin Therapy

<p>Abstract</p> <p>Background</p> <p>Nonylphenol (NP), an environmental organic compound, has been demonstrated to enhance reactive-oxygen species (ROS) synthesis. Chronic exposure to low-dose adenine (AD) has been reported to induce chronic kidney disease (CKD).</p&...

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Main Authors: Yen Chia-Hung, Sun Cheuk-Kwan, Leu Steve, Wallace Christopher, Lin Yu-Chun, Chang Li-Teh, Chen Yung-Lung, Tsa Tzu-Hsien, Kao Ying-Hsien, Shao Pei-Lin, Hsieh Chi-Ying, Chen Yen-Ta, Yip Hon-Kan
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/10/1/147