Mitochondrial DNA mutations provoke dominant inhibition of mitochondrial inner membrane fusion.

Mitochondria are highly dynamic organelles that continuously move, fuse and divide. Mitochondrial dynamics modulate overall mitochondrial morphology and are essential for the proper function, maintenance and transmission of mitochondria and mitochondrial DNA (mtDNA). We have investigated mitochondri...

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Bibliographic Details
Main Authors: Cécile Sauvanet, Stéphane Duvezin-Caubet, Bénédicte Salin, Claudine David, Aurélie Massoni-Laporte, Jean-Paul di Rago, Manuel Rojo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3500310?pdf=render