Evaluation of nitric oxide involvement in effect of lead on dependency to morphine in mice

In the present study, interactions between lead exposure with nitric oxide precursor (L-arginine) or nitric oxide synthase (NOS) inhibitor (L-NAME) on naloxone-induced jumping and diarrhea in morphine-dependent mice were examined. Chronic lead acetate (0.05%) exposure altered naloxone-induced jumpin...

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Bibliographic Details
Main Authors: Mohammad-Reza Zarrindast, Bita Hamidi, Mohammad Sharifzadeh, Mousa Sahebgharani, Soheila Fazli-Tabaei
Format: Article
Language:English
Published: Iran University of Medical Sciences 2010-01-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-18&slc_lang=en&sid=1