Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner.

Quercetin treatment reduces the severity of renal dysplasia in a beta-catenin dependent manner.

Renal dysplasia, the major cause of childhood renal failure, is characterized by defective branching morphogenesis and nephrogenesis. Beta-catenin, a transcription factor and cell adhesion molecule, is markedly increased in the nucleus of kidney cells in human renal dysplasia and contributes to its...

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Bibliographic Details
Main Authors: Joanna Cunanan, Erin Deacon, Kristina Cunanan, Zifan Yang, Antje Ask, Lily Morikawa, Ekaterina Todorova, Darren Bridgewater
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234375

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https://doi.org/10.1371/journal.pone.0234375

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