GOST: A generic ordinal sequential trial design for a treatment trial in an emerging pandemic.

BACKGROUND:Conducting clinical trials to assess experimental treatments for potentially pandemic infectious diseases is challenging. Since many outbreaks of infectious diseases last only six to eight weeks, there is a need for trial designs that can be implemented rapidly in the face of uncertainty....

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Bibliographic Details
Main Authors: John Whitehead, Peter Horby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5360336?pdf=render