Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes

We here report our studies on the reaction with the platinum(II) ion of a nucleoamino acid constituted by the <span style="font-variant: small-caps;">l</span>-2,3-diaminopropanoic acid linked to the thymine nucleobase through a methylenecarbonyl linker. The obtained new platinu...

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Bibliographic Details
Main Authors: Claudia Riccardi, Domenica Capasso, Angela Coppola, Chiara Platella, Daniela Montesarchio, Sonia Di Gaetano, Giovanni N. Roviello, Domenica Musumeci
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceuticals
Subjects:
Pt(II) complexes
nucleoamino acid ligand
NMR spectroscopy
antiproliferative activity
DNA binding studies
CD spectroscopy
Online Access:https://www.mdpi.com/1424-8247/13/10/284

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https://www.mdpi.com/1424-8247/13/10/284

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