Factors that influence the androgen receptor cistrome in benign and malignant prostate cells

The androgen receptor (AR) plays key roles in the development of prostate tissue and the development and progression of prostate cancer (PC). AR guides cytodifferentiation and homeostasis in benign luminal epithelial cells; however, in PC, AR instead drives the uncontrolled proliferation of these ce...

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Bibliographic Details
Main Authors: Ben T. Copeland, Juan Du, Sumanta K. Pal, Jeremy O. Jones
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.12572