Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment

Kirsten rat sarcoma viral oncogene (K-ras) is a well-documented, frequently mutated gene in lung cancer. Since K-ras regulates numerous signaling pathways related to cell survival and proliferation, mutations in this gene are powerful drivers of tumorigenesis and confer prodigious survival advantage...

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Bibliographic Details
Main Authors: Shanshan Deng, Michael J. Clowers, Walter V. Velasco, Marco Ramos-Castaneda, Seyed Javad Moghaddam
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Oncology
Subjects:
lung cancer
inflammation
cytokine
tumor microenvironment
K-ras
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01556/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01556/full

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