Mechanism Study of the Protective Effects of Sodium Tanshinone IIA Sulfonate Against Atorvastatin-Induced Cerebral Hemorrhage in Zebrafish: Transcriptome Analysis

Mechanism Study of the Protective Effects of Sodium Tanshinone IIA Sulfonate Against Atorvastatin-Induced Cerebral Hemorrhage in Zebrafish: Transcriptome Analysis

Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Salvia miltiorrhiza Bunge (Danshen) is a well-known Chinese Materia Medica for treating cerebral vascular and cardiovascular diseases in traditional Chinese medicine. Sodium tanshinone IIA sulfonate (ST...

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Bibliographic Details
Main Authors: Zhong-Yan Zhou, Wai-Rong Zhao, Ying Xiao, Jing Zhang, Jing-Yi Tang, Simon Ming-Yuen Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
sodium tanshinone IIA sulfonate
cerebral hemorrhage
atorvastatin
hypoxia-inducible factor 1
hemoglobin
carbonic anhydrase
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.551745/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.551745/full

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