Novel structurally designed vaccine for S. aureus α-hemolysin: protection against bacteremia and pneumonia.

Staphylococcus aureus (S. aureus) is a human pathogen associated with skin and soft tissue infections (SSTI) and life threatening sepsis and pneumonia. Efforts to develop effective vaccines against S. aureus have been largely unsuccessful, in part due to the variety of virulence factors produced by...

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Main Authors: Rajan P Adhikari, Hatice Karauzum, Jawad Sarwar, Laura Abaandou, Mahta Mahmoudieh, Atefeh R Boroun, Hong Vu, Tam Nguyen, V Sathya Devi, Sergey Shulenin, Kelly L Warfield, M Javad Aman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22701668/?tool=EBI