Zebrafish knock-ins swim into the mainstream

The zebrafish is an increasingly popular model organism for human genetic disease research. CRISPR/Cas9-based approaches are currently used for multiple gene-editing purposes in zebrafish, but few studies have developed reliable ways to introduce precise mutations. Point mutation knock-in using CRIS...

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Bibliographic Details
Main Authors: Sergey V. Prykhozhij, Jason N. Berman
Format: Article
Language:English
Published: The Company of Biologists 2018-10-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/11/10/dmm037515