The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson’s Disease

MicroRNAs (miRNAs) are small double-stranded RNAs that exert a fine-tuning sequence-specific regulation of cell transcriptome. While one unique miRNA regulates hundreds of mRNAs, each mRNA molecule is commonly regulated by various miRNAs that bind to complementary sequences at 3’-untranslated region...

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Bibliographic Details
Main Authors: Simoneide S. Titze-de-Almeida, Cristina Soto-Sánchez, Eduardo Fernandez, James B. Koprich, Jonathan M. Brotchie, Ricardo Titze-de-Almeida
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/841