A randomized controlled trial to determine whether beta-hydroxy-beta-methylbutyrate and/or eicosapentaenoic acid improves diaphragm and quadriceps strength in critically Ill mechanically ventilated patients

A randomized controlled trial to determine whether beta-hydroxy-beta-methylbutyrate and/or eicosapentaenoic acid improves diaphragm and quadriceps strength in critically Ill mechanically ventilated patients

Abstract Background Intensive care unit acquired weakness is a serious problem, contributing to respiratory failure and reductions in ambulation. Currently, there is no pharmacological therapy for this condition. Studies indicate, however, that both beta-hydroxy-beta-methylbutyrate (HMB) and eicosap...

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Bibliographic Details
Main Authors: Gerald S. Supinski, Paul F. Netzel, Philip M. Westgate, Elizabeth A. Schroder, Lin Wang, Leigh Ann Callahan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Critical Care
Subjects:
Diaphragm weakness
Respiratory failure
Mechanical ventilation
Limb muscle weakness
Beta-hydroxy-beta-methylbutyrate
Eicosapentaenoic acid
Online Access:https://doi.org/10.1186/s13054-021-03737-9

Internet

https://doi.org/10.1186/s13054-021-03737-9

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