DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1

Autophagy can protect cancer cells from acute starvation and enhance resistance to chemotherapy. Previously, we reported that autophagy plays a critical role in the survival of dormant, drug resistant ovarian cancer cells using human xenograft models and correlated the up-regulation of autophagy and...

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Bibliographic Details
Main Authors: Margie N. Sutton, Gilbert Y. Huang, Xiaowen Liang, Rajesh Sharma, Albert S. Reger, Weiqun Mao, Lan Pang, Philip J. Rask, Kwangkook Lee, Joshua P. Gray, Amy M. Hurwitz, Timothy Palzkill, Steven W. Millward, Choel Kim, Zhen Lu, Robert C. Bast
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Cancers
Subjects:
autophagy inhibitor
DIRAS3
Beclin1
peptide therapeutic
ARHI
ovarian cancer
Online Access:https://www.mdpi.com/2072-6694/11/4/557

Internet

https://www.mdpi.com/2072-6694/11/4/557

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