Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex

Evolutionary Gain of Dbx1 Expression Drives Subplate Identity in the Cerebral Cortex

Summary: Changes in transcriptional regulation through cis-regulatory elements are thought to drive brain evolution. However, how this impacts the identity of primate cortical neurons is still unresolved. Here, we show that primate-specific cis-regulatory sequences upstream of the Dbx1 gene promote...

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Bibliographic Details
Main Authors: Yoko Arai, Andrzej W. Cwetsch, Eva Coppola, Sara Cipriani, Hidenori Nishihara, Hiroaki Kanki, Yoann Saillour, Betty Freret-Hodara, Annie Dutriaux, Norihiro Okada, Hideyuki Okano, Colette Dehay, Jeannette Nardelli, Pierre Gressens, Tomomi Shimogori, Giuseppe D’Onofrio, Alessandra Pierani
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719311842

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http://www.sciencedirect.com/science/article/pii/S2211124719311842

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