Dibutyltin Compounds Effects on PPARγ/RXRα Activity, Adipogenesis, and Inflammation in Mammalians Cells

Dibutyltin Compounds Effects on PPARγ/RXRα Activity, Adipogenesis, and Inflammation in Mammalians Cells

Organotins are a group of chemical compounds that have a tin atom covalently bound to one or more organic groups. The best-studied organotin is tributyltin chloride, which is an environmental pollutant and an endocrine disruptor. Tributyltin chloride has been shown to bind to PPARγ/RXRα and induces...

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Bibliographic Details
Main Authors: Flora A. Milton, Mariella G. Lacerda, Simone B. P. Sinoti, Pedro G. Mesquita, Dileesh Prakasan, Michella S. Coelho, Caroline L. de Lima, Alexandre G. Martini, Gabriela T. Pazzine, Maria de F. Borin, Angelica A. Amato, Francisco de A. R. Neves
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
tributyltin
dibutyltin
peroxisome proliferator activated receptor gamma
adipogenesis
proinflammatory genes
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00507/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00507/full

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