The molecular mechanism of ion-dependent gating in secondary transporters.

LeuT-like fold Na-dependent secondary active transporters form a large family of integral membrane proteins that transport various substrates against their concentration gradient across lipid membranes, using the free energy stored in the downhill concentration gradient of sodium ions. These transpo...

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Bibliographic Details
Main Authors: Chunfeng Zhao, Sergei Yu Noskov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3812048?pdf=render