Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells

Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells

Lysophosphatidylcholine (lyso-PC) and arachidonate are products of phosphatidylcholine hydrolysis by phospholipase A2. In this study, the modulation of arachidonate release by exogenous lyso-PC in rat heart myoblastic H9c2 cells was examined. Incubation of H9c2 cells with lyso-PC resulted in an enha...

Full description

Bibliographic Details
Main Authors: Leonard S. Golfman, Norman J. Haughey, Jason T. Wong, Jenny Y. Jiang, Douglas Lee, Jonathan D. Geiger, Patrick C. Choy
Format: Article
Language:English
Published: Elsevier 1999-10-01
Series:Journal of Lipid Research
Subjects:
lysophospholipids
calcium transport
myoblasts
MAPK
PKC
sarcolemma
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520348987

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520348987

Similar Items