CircFAM13B promotes the proliferation of hepatocellular carcinoma by sponging miR-212, upregulating E2F5 expression and activating the P53 pathway

CircFAM13B promotes the proliferation of hepatocellular carcinoma by sponging miR-212, upregulating E2F5 expression and activating the P53 pathway

Abstract Background Most of the biological functions of circular RNAs (circRNAs) and the potential underlying mechanisms in hepatocellular carcinoma (HCC) have not yet been discovered. Methods In this study, using circRNA expression data from HCC tumor tissues and adjacent tissues from the Gene Expr...

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Bibliographic Details
Main Authors: Ying Xie, Xiaofeng Hang, Wensheng Xu, Jing Gu, Yuanjing Zhang, Jianrong Wang, Xiucui Zhang, Xinghao Cao, Junjie Zhan, Junxue Wang, Jianhe Gan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cancer Cell International
Subjects:
circFAM13B
miR-212
E2F5
P53
HCC
Online Access:https://doi.org/10.1186/s12935-021-02120-6

Internet

https://doi.org/10.1186/s12935-021-02120-6

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