Animal, Herb, and Microbial Toxins for Structural and Pharmacological Study of Acid-Sensing Ion Channels

Animal, Herb, and Microbial Toxins for Structural and Pharmacological Study of Acid-Sensing Ion Channels

Acid-sensing ion channels (ASICs) are of the most sensitive molecular sensors of extracellular pH change in mammals. Six isoforms of these channels are widely represented in membranes of neuronal and non-neuronal cells, where these molecules are involved in different important regulatory functions,...

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Bibliographic Details
Main Authors: Dmitry I. Osmakov, Timur A. Khasanov, Yaroslav A. Andreev, Ekaterina N. Lyukmanova, Sergey A. Kozlov
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
acid-sensing ion channels
natural compounds
ligand receptor interaction
structural features
analgesia
drug development
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00991/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00991/full

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