Ovalbumin-Derived Peptides Activate Retinoic Acid Signalling Pathways and Induce Regulatory Responses Through Toll-Like Receptor Interactions

Ovalbumin-Derived Peptides Activate Retinoic Acid Signalling Pathways and Induce Regulatory Responses Through Toll-Like Receptor Interactions

This study investigates the potential of a hydrolysate of ovalbumin with pepsin (OP) to preclude Th2-type immunity by the enhancement of tolerogenic dendritic cells (DCs) and regulatory T (Treg) cells. Through Toll-like receptor (TLR) stimulation, OP enhances the retinoic acid pathway on DCs by mean...

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Bibliographic Details
Main Authors: Mónica Martínez-Blanco, Leticia Pérez-Rodríguez, Daniel Lozano-Ojalvo, Elena Molina, Rosina López-Fandiño
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Nutrients
Subjects:
dendritic cells
peptide immunotherapy
regulatory t cells
retinoic acid
toll like receptors
Online Access:https://www.mdpi.com/2072-6643/12/3/831

Internet

https://www.mdpi.com/2072-6643/12/3/831

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