Modulation of Bcl-x Alternative Splicing Induces Apoptosis of Human Hepatic Stellate Cells
Liver fibrosis is a major cause of morbidity and mortality worldwide due to chronic viral hepatitis and, more recently, from fatty liver diseases. Activation and proliferation of hepatic stellate cells (HSCs) represent a key aspect of fibrogenesis and are associated with progressive reduction of HSC...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2016/7478650 |