Differential regulation of H3S10 phosphorylation, mitosis progression and cell fate by Aurora Kinase B and C in mouse preimplantation embryos

Differential regulation of H3S10 phosphorylation, mitosis progression and cell fate by Aurora Kinase B and C in mouse preimplantation embryos

ABSTRACT Coordination of cell division and cell fate is crucial for the successful development of mammalian early embryos. Aurora kinases are evolutionarily conserved serine/threonine kinases and key regulators of mitosis. Aurora kinase B (AurkB) is ubiquitously expressed while Aurora kinase C (Aurk...

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Bibliographic Details
Main Authors: Wenzhi Li, Peizhe Wang, Bingjie Zhang, Jing Zhang, Jia Ming, Wei Xie, Jie Na
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:Protein & Cell
Subjects:
Aurora kinase
mouse preimplantation embryo
cell fate
development
mitosis
Online Access:http://link.springer.com/article/10.1007/s13238-017-0407-5

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http://link.springer.com/article/10.1007/s13238-017-0407-5

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