Development and characterization of sphingosine 1-phosphate receptor 1 monoclonal antibody suitable for cell imaging and biochemical studies of endogenous receptors.

Although sphingosine-1-phosphate receptor 1 (S1P1) has been shown to trigger several S1P targeted functions such as immune cell trafficking, cell proliferation, migration, or angiogenesis, tools that allow the accurate detection of endogenous S1P1 localization and trafficking remain to be obtained a...

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Bibliographic Details
Main Authors: Franck Talmont, Lionel Moulédous, Marion Baranger, Anne Gomez-Brouchet, Jean-Marie Zajac, Clarence Deffaud, Olivier Cuvillier, Anastassia Hatzoglou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213203