Arsenic leads to autophagy of keratinocytes by increasing aquaporin 3 expression

Abstract Exposure to arsenic, a ubiquitous metalloid on Earth, results in human cancers. Skin cancer is the most common arsenical cancers. Both autophagy and aquaporin pathway are known to promote carcinogenesis. However, the mechanisms by which arsenic regulates aquaporin and autophagy in arsenical...

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Bibliographic Details
Main Authors: Sebastian Yu, Ling-Hau Li, Chih-Hung Lee, Palaniraja Jeyakannu, Jeh-Jeng Wang, Chien-Hui Hong
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96822-6