Thinking Outside the Box: Innate- and B Cell-Memory Responses as Novel Protective Mechanisms Against Tuberculosis

Thinking Outside the Box: Innate- and B Cell-Memory Responses as Novel Protective Mechanisms Against Tuberculosis

Tuberculosis (TB) is currently the deadliest infectious disease worldwide. Failure to create a highly effective vaccine has limited the control of the TB epidemic. Historically, the vaccine field has relied on the paradigm that IFN-γ-mediated CD4+ T cell memory responses are the principal correlate...

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Bibliographic Details
Main Authors: José Alberto Choreño-Parra, León Islas Weinstein, Edmond J. Yunis, Joaquín Zúñiga, Rogelio Hernández-Pando
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium tuberculosis
trained immunity
B-cells
memory-like NK cells
ILCs
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00226/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00226/full

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