Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes

Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes

Immunotherapies harnessing T cell immunity have shown remarkable clinical success for the management of cancer. However, only a proportion of patients benefit from these treatments. The presence of type I interferon (IFN) within the tumor microenvironment is critical for driving effective tumor-spec...

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Bibliographic Details
Main Authors: Anthony C. Buzzai, Teagan Wagner, Katherine M. Audsley, Hannah V. Newnes, Lucy W. Barrett, Samantha Barnes, Ben C. Wylie, Shane Stone, Alison McDonnell, Vanessa S. Fear, Bree Foley, Jason Waithman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
interferon subtypes
adoptive cell therapy
tumor microenvironment
CD8+ T cells
immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00542/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00542/full

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