IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+ monocytes

IL-7δ5 protein is expressed in human tissues and induces expression of the oxidized low density lipoprotein receptor 1 (OLR1) in CD14+ monocytes

Objectives: The 6-exon-spanning ‘canonical’ Interleukin-7 (IL-7c) is a non-redundant cytokine in human T-cell homeostasis that undergoes extensive alternative pre-mRNA splicing. The IL-7 gene variant lacking, exon 5 (IL-7δ5), exhibits agonistic effects as compared to IL-7c. We studied in this report...

Full description

Bibliographic Details
Main Authors: Lalit Rane, Sayma Rahman, Isabelle Magalhaes, Aditya Ambati, Jan Andersson, Alimuddin Zumla, Susanna Brighenti, Markus J. Maeurer
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:International Journal of Infectious Diseases
Subjects:
Interleukin-7
IL-7&delta
5 protein
alternative splicing
OLR1
Tuberculosis
M. tuberculosis
Online Access:http://www.sciencedirect.com/science/article/pii/S120197121730084X

Internet

http://www.sciencedirect.com/science/article/pii/S120197121730084X

Similar Items