Vesicular LL-37 contributes to inflammation of the lesional skin of palmoplantar pustulosis.

"Pustulosis palmaris et plantaris", or palmoplantar pustulosis (PPP), is a chronic pustular dermatitis characterized by intraepidermal palmoplantar pustules. Although early stage vesicles (preceding the pustular phase) formed in the acrosyringium contain the antimicrobial peptides cathelic...

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Main Authors: Masamoto Murakami, Takaaki Kaneko, Teruaki Nakatsuji, Kenji Kameda, Hidenori Okazaki, Xiuju Dai, Yasushi Hanakawa, Mikiko Tohyama, Akemi Ishida-Yamamoto, Koji Sayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199729?pdf=render