Effects of valsartan on morphine tolerance and dependence in rats

Effects of valsartan on morphine tolerance and dependence in rats

Background and purpose: Opiates are traditionally used for the treatment of pain. Chronic consumption of opiates such as morphine (MOR) induces tolerance and dependence. This study aimed to investigate the effects of valsartan (VAL), as an angiotensin II receptor blocker, on the induction and expres...

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Bibliographic Details
Main Authors: Ayat Kaeidi, Morteza Amirteimoury, Mohammad-Saleh Zare, Amirhossein Nazari, Elham Hakimizadeh, Jalal Hassanshahi, Iman Fatemi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
morphine; physical dependence; rat; tolerance; valsartan
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=3;spage=286;epage=293;aulast=Kaeidi

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=3;spage=286;epage=293;aulast=Kaeidi

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