Advances in the Role of Leucine-Sensing in the Regulation of Protein Synthesis in Aging Skeletal Muscle

Skeletal muscle anabolic resistance (i.e., the decrease in muscle protein synthesis (MPS) in response to anabolic stimuli such as amino acids and exercise) has been identified as a major cause of age-related sarcopenia, to which blunted nutrition-sensing contributes. In recent years, it has been sug...

Full description

Bibliographic Details
Main Authors: Yan Zhao, Jason Cholewa, Huayu Shang, Yueqin Yang, Xiaomin Ding, Qianjin Wang, Quansheng Su, Nelo Eidy Zanchi, Zhi Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.646482/full