ZFX Controls Propagation and Prevents Differentiation of Acute T-Lymphoblastic and Myeloid Leukemia

ZFX Controls Propagation and Prevents Differentiation of Acute T-Lymphoblastic and Myeloid Leukemia

Tumor-propagating cells in acute leukemia maintain a stem/progenitor-like immature phenotype and proliferative capacity. Acute myeloid leukemia (AML) and acute T-lymphoblastic leukemia (T-ALL) originate from different lineages through distinct oncogenic events such as MLL fusions and Notch signaling...

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Bibliographic Details
Main Authors: Stuart P. Weisberg, Matthew R. Smith-Raska, Jose M. Esquilin, Ji Zhang, Teresita L. Arenzana, Colleen M. Lau, Michael Churchill, Haiyan Pan, Apostolos Klinakis, Jack E. Dixon, Leonid A. Mirny, Siddhartha Mukherjee, Boris Reizis
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714000084

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http://www.sciencedirect.com/science/article/pii/S2211124714000084

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