The Integrated Landscape of Biological Candidate Causal Genes in Coronary Artery Disease

The Integrated Landscape of Biological Candidate Causal Genes in Coronary Artery Disease

BackgroundGenome-wide association studies (GWASs) have identified more than 150 genetic loci that demonstrate robust association with coronary artery disease (CAD). In contrast to the success of GWAS, the translation from statistical signals to biological mechanism and exploration of causal genes fo...

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Bibliographic Details
Main Authors: Qiwen Zheng, Yujia Ma, Si Chen, Qianzi Che, Dafang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
coronary artery disease
genome-wide association studies
prioritize
causal genes
expression quantitative trait locus
protein–protein interaction
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00320/full

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https://www.frontiersin.org/article/10.3389/fgene.2020.00320/full

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