Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis.

Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis.

BACKGROUND:Dysregulation of Fractalkine (CX3CL1) and its receptor CX3CR1 has been linked to the pathobiology of chronic inflammatory conditions. We explored CX3CL1 in systemic sclerosis (SSc) related progressive interstitial lung disease (ILD) and pulmonary hypertension (PH) in two different but com...

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Bibliographic Details
Main Authors: Anna-Maria Hoffmann-Vold, Stephen Samuel Weigt, Vyacheslav Palchevskiy, Elizabeth Volkmann, Rajan Saggar, Ning Li, Øyvind Midtvedt, May Brit Lund, Torhild Garen, Michael C Fishbein, Abbas Ardehali, David J Ross, Thor Ueland, Pål Aukrust, Joseph P Lynch, Robert M Elashoff, Øyvind Molberg, John A Belperio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6245508?pdf=render

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http://europepmc.org/articles/PMC6245508?pdf=render

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