Expression of Two Foreign Genes from the Optimal Insertion Sites of Newcastle Disease Virus Vector for Use as a Multivalent Vaccine and Gene Therapy Vector

Expression of Two Foreign Genes from the Optimal Insertion Sites of Newcastle Disease Virus Vector for Use as a Multivalent Vaccine and Gene Therapy Vector

Many Newcastle disease virus (NDV) strains have been developed as vectors to express a foreign gene (FG) for vaccine and gene therapy purposes. A majority of these NDV vectors express only a single FG or two FGs from suboptimal insertion sites in the NDV genome, obtaining various levels of FG expres...

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Bibliographic Details
Main Authors: Lei He, Zhenyu Zhang, Qingzhong Yu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
NDV
foreign genes
GFP and RFP
optimal insertion sites
co-expression
multivalent vector
Online Access:https://www.mdpi.com/2504-3900/50/1/9

Internet

https://www.mdpi.com/2504-3900/50/1/9

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