Sequence embedding for fast construction of guide trees for multiple sequence alignment

<p>Abstract</p> <p>Background</p> <p>The most widely used multiple sequence alignment methods require sequences to be clustered as an initial step. Most sequence clustering methods require a full distance matrix to be computed between all pairs of sequences. This requir...

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Bibliographic Details
Main Authors: Wilm Andreas, Shi Weifeng, Sievers Fabian, Blackshields Gordon, Higgins Desmond G
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Algorithms for Molecular Biology
Online Access:http://www.almob.org/content/5/1/21