Apamin Suppresses LPS-Induced Neuroinflammatory Responses by Regulating SK Channels and TLR4-Mediated Signaling Pathways

Apamin Suppresses LPS-Induced Neuroinflammatory Responses by Regulating SK Channels and TLR4-Mediated Signaling Pathways

Neuroinflammation plays a vital role in neurodegenerative conditions. Microglia are a key component of the neuroinflammatory response. There is a growing interest in developing drugs to target microglia and thereby control neuroinflammatory processes. Apamin (APM) is a specifically selective antagon...

Full description

Bibliographic Details
Main Authors: Jihyun Park, Kyung Mi Jang, Kwan-Kyu Park
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
neuroinflammation
CaMKII
TLR4
apamin
NF-κB
STAT3
Online Access:https://www.mdpi.com/1422-0067/21/12/4319

Internet

https://www.mdpi.com/1422-0067/21/12/4319

Similar Items