Raising intracellular calcium attenuates neuronal apoptosis triggered by staurosporine or oxygen-glucose deprivation in the presence of glutamate receptor blockade

The relationship between intracellular Ca2+ ([Ca2+]i) regulation and programmed cell death is not well-defined; both increases and decreases in [Ca2+]i have been observed in cells undergoing apoptosis. We determined [Ca2+]i in cultured murine cortical neurons undergoing apoptosis after exposure to s...

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Bibliographic Details
Main Authors: Lorella M.T Canzoniero, Debra J Babcock, Frank J Gottron, Margaret C Grabb, Pat Manzerra, B.Joy Snider, Dennis W Choi
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Neurobiology of Disease
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Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103002110