High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth

Myxoid liposarcoma (MLS) is a soft tissue sarcoma characterized by a recurrent t(12;16) translocation. Although tumors are initially radio- and chemosensitive, the management of inoperable or metastatic MLS can be challenging. Therefore, our aim was to identify novel targets for systemic therapy. We...

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Bibliographic Details
Main Authors: Marieke A. de Graaff, Shruti Malu, Irma Guardiola, Alwine B. Kruisselbrink, Yvonne de Jong, Willem E. Corver, H. Gelderblom, Patrick Hwu, Torsten O. Nielsen, Alexander J. Lazar, Neeta Somaiah, Judith V.M.G. Bovée
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317300803