A trans-eQTL network regulates osteoclast multinucleation and bone mass

A trans-eQTL network regulates osteoclast multinucleation and bone mass

Functional characterisation of cell-type-specific regulatory networks is key to establish a causal link between genetic variation and phenotype. The osteoclast offers a unique model for interrogating the contribution of co-regulated genes to in vivo phenotype as its multinucleation and resorption ac...

Full description

Bibliographic Details
Main Authors: Marie Pereira, Jeong-Hun Ko, John Logan, Hayley Protheroe, Kee-Beom Kim, Amelia Li Min Tan, Peter I Croucher, Kwon-Sik Park, Maxime Rotival, Enrico Petretto, JH Duncan Bassett, Graham R Williams, Jacques Behmoaras
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
mouse
rat
bone
osteoclast
network
Online Access:https://elifesciences.org/articles/55549

Internet

https://elifesciences.org/articles/55549

Similar Items