Search for independent (β/α)4 subdomains in a (β/α)8 barrel β-glucosidase.

Proteins that fold as (β/α)8 barrels are thought to have evolved from half-barrels that underwent duplication and fusion events. The evidence is particularly clear for small barrels, which have almost identical halves. Additionally, computational calculations of the thermodynamic stability of these...

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Bibliographic Details
Main Authors: Vitor M Almeida, Maira A Frutuoso, Sandro R Marana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5770038?pdf=render