Is adalimumab protective in ischemia-reperfusion injury in lung?

Is adalimumab protective in ischemia-reperfusion injury in lung?

Objective(s): Increasing cytokines and reactive oxygen species (ROS) during ischemia reperfusion (I-R) leads to the lung damage. Adalimumab (Ada) is a potent tumor necrosis factor-alpha (TNF-α) inhibitor agent. We aimed to evaluate whether Ada would prevent the lung tissue from damage development ov...

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Bibliographic Details
Main Authors: Aysel Kurt, Levent Tumkaya, Yildiray Kalkan, Hasan Turut, Medine Cumhur Cure, Erkan Cure, Ibrahim Sehitoglu, Hacer Bilgin, Mustafa Usta
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Adalimumab
Endothelin-1
Ischemia reperfusion
Lung injury
Tumor necrosis factor-alpha
Online Access:http://ijbms.mums.ac.ir/pdf_6047_94fb0d10ddd4fd5c23a5fec11109ecb0.html

Internet

http://ijbms.mums.ac.ir/pdf_6047_94fb0d10ddd4fd5c23a5fec11109ecb0.html

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