Sera from remitting and secondary progressive multiple sclerosis patients disrupt the blood-brain barrier.

Sera from remitting and secondary progressive multiple sclerosis patients disrupt the blood-brain barrier.

BACKGROUND: Pathological destruction of blood-brain barrier (BBB) has been thought to be the initial key event in the process of developing multiple sclerosis (MS). The purpose of the present study was to clarify the possible molecular mechanisms responsible for the malfunction of BBB by sera from r...

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Bibliographic Details
Main Authors: Fumitaka Shimizu, Ayako Tasaki, Yasuteru Sano, Mihua Ju, Hideaki Nishihara, Mariko Oishi, Michiaki Koga, Motoharu Kawai, Takashi Kanda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3970956?pdf=render

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http://europepmc.org/articles/PMC3970956?pdf=render

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