Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration

Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration

The intervertebral disc is an important mechanical structure that allows range of motion of the spinal column. Degeneration of the intervertebral disc – incited by aging, traumatic insult, genetic predisposition, or other factors – is often defined by functional and structural changes in the tissue,...

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Bibliographic Details
Main Authors: ZI Johnson, ZR Schoepflin, H Choi, IM Shapiro, MV Risbud
Format: Article
Language:English
Published: AO Research Institute Davos 2015-09-01
Series:European Cells & Materials
Subjects:
Intervertebral disc
nucleus pulposus
cytokines
extracellular matrix
tumour necrosis factor
interleukin-1
Toll-like receptor
Online Access:http://www.ecmjournal.org/papers/vol030/pdf/v030a08.pdf

Internet

http://www.ecmjournal.org/papers/vol030/pdf/v030a08.pdf

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