Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1

Cancer therapeutics: Extending a drug’s reach A new drug that blocks heat shock proteins (HSPs), helper proteins that are co-opted by cancer cells to promote tumor growth, shows promise for cancer treatment. Several drugs have targeted HSPs, since cancer cells are known to hijack these helper protei...

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Bibliographic Details
Main Authors: Hye-Kyung Park, Nam Gu Yoon, Ji-Eun Lee, Sung Hu, Sora Yoon, So Yeon Kim, Jun-Hee Hong, Dougu Nam, Young Chan Chae, Jong Bae Park, Byoung Heon Kang
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0360-x