Genomic, Microbial and Immunological Microenvironment of Colorectal Polyps

Genomic, Microbial and Immunological Microenvironment of Colorectal Polyps

Colorectal cancer (CRC) develops from pre-cancerous cellular lesions in the gut epithelium, known as polyps. Polyps themselves arise through the accumulation of mutations that disrupt the function of key tumour suppressor genes, activate proto-oncogenes and allow proliferation in an environment wher...

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Bibliographic Details
Main Authors: Benita C. Y. Tse, Zoe Welham, Alexander F. Engel, Mark P. Molloy
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
colorectal polyps
adenoma
colorectal carcinoma
microbiome
immunogenic
mutational burden
Online Access:https://www.mdpi.com/2072-6694/13/14/3382

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https://www.mdpi.com/2072-6694/13/14/3382

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