Therapeutic development of group B Streptococcus meningitis by targeting a host cell signaling network involving EGFR

Therapeutic development of group B Streptococcus meningitis by targeting a host cell signaling network involving EGFR

Abstract Group B Streptococcus (GBS) remains the most common Gram‐positive bacterium causing neonatal meningitis and GBS meningitis continues to be an important cause of mortality and morbidity. In this study, we showed that GBS penetration into the brain occurred initially in the meningeal and cort...

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Bibliographic Details
Main Authors: Ningyu Zhu, Chengxian Zhang, Atish Prakash, Zheng Hou, Wei Liu, Weifeng She, Andrew Morris, Kwang Sik Kim
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:EMBO Molecular Medicine
Subjects:
blood–brain barrier
CysLTs
EGFR
GBS meningitis
S1P
Online Access:https://doi.org/10.15252/emmm.202012651

Internet

https://doi.org/10.15252/emmm.202012651

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