The Vacuolar Ca2+ ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis

The Vacuolar Ca2+ ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis

Maintenance of Ca2+ homeostasis is important for fungal cells to respond to a multitude of stresses, as well as antifungal treatment, and for virulence in animal models. Here, we demonstrate that a P-type ATPase, Pmc1p, is required for Candida albicans to respond to a variety of stresses, affects az...

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Bibliographic Details
Main Authors: Arturo Luna-Tapia, Christian DeJarnette, Emily Sansevere, Parker Reitler, Arielle Butts, Kirk E. Hevener, Glen E. Palmer
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
Candida albicans
Pmc1p
Vcx1p
calcium
pathogenesis
vacuole
Online Access:https://doi.org/10.1128/mSphere.00715-18

Internet

https://doi.org/10.1128/mSphere.00715-18

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